Texas A&M University Institute of Advanced Studies Mobile menu

Michael Moore

Michael Moore

Howdy! My name is Michael Moore, and I am a fourth year Ph.D. graduate student in the Department of Chemistry at Texas A&M University. Being awarded the TIAS HEEP fellowship last year was a tremendous honor and undoubtedly helped further advance my research. My project, which is focused on determining the molecular structures of small metal-containing compounds found in mitochondria, has made some excellent progress over the course of a year. Although these metal species have not been well characterized, they are hypothesized to serve vital biological functions in the context of cellular metal ion trafficking, metabolism, and storage. Elucidating the structures of these metal complexes is absolutely essential because they could open the door to the development of therapeutic compounds that would treat or alleviate symptoms of various metal-associated diseases.

Unfortunately, I was not able to collaborate or receive guidance from Faculty Fellow Dr. Richard Holm due to unforeseen circumstances that occurred at the start of the fellowship. Hopefully, in the not-so distant future, there will be an opportunity for us to meet and discuss my project in greater detail.

The work I have completed throughout this fellowship has resulted in the recent publication of a review article titled “Labile Low-Molecular-Mass Metal Complexes in Mitochondria: Trials and Tribulations of a Burgeoning Field” in Biochemistry. Additionally, I’ll be presenting my work at the BASF symposium held at Texas A&M next month in August.

Major

Chemistry

Graduation Year

August 2017

Degree Type

Ph.D.

Fellowship Year(s)

'15 - '16

Previous Education

B.S. in Chemistry (Biology & Philosophy minors) - Gannon University - '11

Advisor

P. Lindahl

Journal Articles

1. Cockrell, A.C., McCormick, S.P., Moore, M.J., Chakrabarti, M., and Lindahl, P.A. (2014). Mössbauer, EPR, and Modeling Study of Iron Trafficking and Regulation in Δccc1 and CCC1-up Saccharomyces cerevisiae. Biochemistry, 53, 2926 – 2940.

2. McCormick, S.P., Moore, M.J., and Lindahl, P.A. (2015). Detection of Labile Low-Molecular-Mass Transition Metal Complexes in Mitochondria. Biochemistry, 54, 3442 – 3453.

3. Lindahl, P.A. and Moore, M.J. (2016) Labile Low-Molecular-Mass Metal Complexes in Mitochondria: Trials and Tribulations of a Burgeoning Field. Biochemistry, 55(30), 4140 – 4153.

Publications

1. http://pubs.acs.org/doi/full/10.1021/bi500002n

2. http://pubs.acs.org/doi/abs/10.1021/bi5015437?journalCode=bichaw

3. http://pubs.acs.org/doi/abs/10.1021/acs.biochem.6b00216